Fat Freddy's Cat began life as a footnote strip to the Freak Brothers and later appeared in many comics of his own. He is often to be found sleeping on the unfortunate Fat Freddy's head. His constant battles with the never-ending army of roaches out for world domination drive him to distraction, as does Fat Freddy's never-ending failure to feed him or empty his kitty litter box.

This cat has variously gone travelling to Mexico, saved the world from alien invasion and worked as a government agent in Washington trying to save the world from the "hee hee hee" drug.

The Omnibus contains reprints of The Adventures of Fat Freddy's Cat #1-7 and The Fabulous Furry Freak Brothers #1-6